The story of Manolo’s journey (voiced by Diego Luna), a young man who should choose between satisfying his family’s hope or following his want. When he cannot decide it yet, Manolo meets a beautiful girl named Maria (Zoe Saldana). Before exploring what he feels to Maria, suddenly Manolo is beaten by a snake that makes him losing his consciousness.
When he wakes up, Manolo is in the spirits world he even does not know. Now Manolo will have a fantastic adventure passing three worlds and face his fear for the sake of love and his choice.